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Four pathways, each with a
defined decision point

Every pathway has a stage at which we stop and reassess against objective measurements — not against how optimistic anyone is feeling.

Pathway Volume 2025

Joint & cartilage44%
Soft tissue & tendon28%
Bone & fracture17%
Wound & dermal11%
Pathway A

Joint & cartilage

Early to moderate osteoarthritis of the knee, hip or shoulder; cartilage defects; persistent post-injury joint pain.

  1. Week 0

    Assessment & imaging

    Weight-bearing X-ray and MRI, functional scoring, and a walking-distance baseline we can measure against later.

  2. Week 1

    Decision point

    Grade 4 joint space loss usually means surgery serves you better than biologics. We will say so.

    Stop / proceed gate
  3. Week 2

    Harvest & therapy

    Bone marrow or adipose harvest, GMP processing and intra-articular delivery under ultrasound guidance, in a single day.

  4. Week 3–12

    Structured rehabilitation

    Loading protocol supervised by physiotherapy. This phase matters at least as much as the injection.

  5. Month 3

    Objective review

    Repeat functional scoring. If there is no measurable change, we say so and discuss alternatives rather than selling a second round.

44% of cases 3 moto first review
28% of cases
Pathway B

Soft tissue & tendon

Chronic tendinopathy, partial tears, and post-surgical soft tissue healing that has plateaued.

  1. Week 0

    Ultrasound assessment

    Dynamic ultrasound to characterise the lesion, plus load testing to establish a functional baseline.

  2. Week 1

    Decision point

    Full-thickness tears go to surgical review, not to biologics. Partial lesions proceed.

    Stop / proceed gate
  3. Week 2

    Peripheral blood harvest

    Autologous blood-derived preparation, processed to a standardised platelet concentration and delivered under ultrasound guidance.

  4. Week 2–10

    Progressive loading

    Graded eccentric loading programme. Rest alone does not heal tendon; controlled load does.

  5. Month 3

    Objective review

    Repeat ultrasound and load testing against your week-0 baseline.

Pathways C & D

Bone, and wound repair

Lower volume, more specialised, and usually run jointly with your referring surgeon.

Pathway C — Bone & fracture

Non-union and delayed-union fractures, critical-size defects and post-resection bone loss.

  1. Step 1

    CT assessment

    Defect volume and vascularity assessed jointly with the referring surgeon.

  2. Step 2

    Scaffold selection

    Matched to defect geometry and expected load-bearing demand.

  3. Step 3

    Combined procedure

    Cell-seeded scaffold implanted, usually during a planned surgical episode.

  4. Step 4

    Serial imaging

    Union assessed radiographically at 6, 12 and 24 weeks.

Pathway D — Wound & dermal

Chronic non-healing wounds, diabetic foot ulceration and hypertrophic scarring.

  1. Step 1

    Wound assessment

    Perfusion, infection status and glycaemic control reviewed first — all three must be addressed before cells can help.

  2. Step 2

    Decision point

    Untreated infection or critical ischaemia stops the pathway until resolved.

  3. Step 3

    Adipose-derived therapy

    Applied topically or by peri-wound injection, with standard dressing care continuing throughout.

  4. Step 4

    Weekly measurement

    Planimetric wound area tracked weekly for twelve weeks.

Which pathway applies to you?

Send your history and imaging and we will tell you which pathway fits — or whether none of them does.

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